The Turd Nerds discuss treatment strategies for CFO (Candida fungal overgrowth). They start by emphasizing the importance of foundations such as sleep, exercise, and stress management. They also highlight the significance of nutrient deficiencies, including zinc, magnesium, iron, and vitamin A. The hosts then explore the use of pharmaceuticals and herbs for treating CFO, with a focus on antifungal medications like nystatin and fluconazole, as well as broad-spectrum antimicrobial herbs like Coptis and Neem. They provide insights into dosing, potential drug interactions, and the pros and cons of each approach.