Updates and research on celiac disease, including the importance of performing four or more biopsies for diagnosis, disparities in testing and treatment based on race and geography, the limitations of a gluten-free diet, and potential future treatments. They also touch on the role of the microbiome, immune modulation, and the impact of food insecurity on celiac patients. The episode concludes with a discussion on the need for a holistic approach to gut health and the importance of considering hormones, immune regulation, and the gut-brain connection.